Journal of Animal Breeding and Genomics (J Anim Breed Genom)
Taebin Kim1, Minsu Go1,2, Dayeon Kang1,2, and Jaemin Kim1,2,3*
1Department of Animal Science and Biotechnology, Gyeongsang National University
2Division of Applied Life Science (BK21 Four), Gyeongsang National University
3Institute of Agriculture and Life Sciences, Gyeongsang National University, Jinju 660-701, Korea
Correspondence to Jaemin Kim, E-mail: jmkim85@gnu.ac.kr
Volume 7, Number 1, Pages 9-15, March 2023.
Journal of Animal Breeding and Genomics 2023, 7(1), 9-15. https://doi.org/10.12972/jabng.20230002
Received on 12 December, 2022, Revised on 22 March, 2023, Accepted on 28 March, 2023, Published on 31 March, 2023.
Copyright © 2023 Korean Society of Animal Breeding and Genetics.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0).
The process of commensal domestication of cats from their ancestor wildcats (Felis silvestris) is not well understood. To identify the genetic underpinnings of cat domestication, we analyzed 46 whole genome sequences (WGS) comprising 3 wildcat species and 16 cat breeds, documenting over 34 million single nucleotide polymorphisms (SNPs). We first showed clear evidence of genomic divergence of domestic cats and wildcats. A genomic comparison between domestic cats and wildcats revealed evidence of genetic selection of underlying neurological functions, nutrient metabolism, and coat patterns, mirroring their historical roles of domestic cats and morphological and behavioral differentiation from wild progenitors.
domestication, domestic cats, wildcats, positive selection, genome
The authors declare that they have no conflicting interests.
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