Journal of Animal Breeding and Genomics (J Anim Breed Genom)
Ji-suk Yu1, Do-Hyun Kim2,, Hak-kyo Lee2, and Jae-Don Oh2*
1Dept of Agriculture and Livestock Food Convergence, Jeonbuk National University, Jeonju 54896, Korea
2Dept of Animal Biotechnology, Jeonbuk National University, Jeonju 54896, Korea
Correspondence to Jae-Don Oh, E-mail: oh5ow@naver.com
Volume 6, Number 4, Pages 221-226, December 2022.
Journal of Animal Breeding and Genomics 2022, 6(4), 221-226. https://doi.org/10.12972/jabng.20220023
Received on December 02, 2022, Revised on December 05, 2022, Accepted on December 09, 2021, Published on December 31, 2022.
Copyright © 2022 Korean Society of Animal Breeding and Genetics.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0).
This study was conducted with the Hanwoo SNP chip (50k_v1) analysis to investigate genotypes of SNPs of Hanwoo (Korean native cattle) in Jeollabuk-do and extent of linkage disequilibrium (LD) among SNP markers. Genomic DNA for genotyping was extracted from the hair root samples of Hanwoo cows (n=1,523). A total of 52,195 SNPs were obtained and 11,056 unnecessary SNPs were removed through the QC process, and a total of 41,139 SNPs were used for LD analysis. The total length of the SNP markers used in the analysis was 2,500 Mb, the mean of minor allele frequency was 0.27 and the average interval distances of adjacent SNP markers by each chromosome was 0.0463 to 0.0725. The results of this study which confirmed by using Hanwoo in Jeollabuk-do, showed a pattern similar to previously reported studies for Hanwoo. The r 2 value was 0.234 for the SNP distance between 0 and 50 Kb and was 0.068 for distance between 150 and 200 Kb. Therefore this study could be utilized as baseline data using genetic improvement for Hanwoo industry.
Linkage Disequilibrium, Hanwoo, SNP chip, Jellabuk-do, Genetic diversity
본 연구는 농촌진흥청(PJ01621803)의 지원으로 수행되었다.
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