Journal of Animal Breeding and Genomics (J Anim Breed Genom)
Heegun Lee1,2†, Sangwon Yoon1,2†, Dain Lee1, Jong-Won Park1, Hyo Sun Jung1, Julan Kim1, Hyerim Yang1, Seung Hwan Lee3, Jeong-Ho Lee1*
1Fish Genetics and Breeding Research Center, National Institute of Fisheries Science, Geoje 53334, Korea
2Department of Bio-AI Convergence, Chungnam National University, Daejeon 34134, Korea
3Division of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea
Correspondence to Jeong-Ho Lee, E-mail: jhlee7124@korea.kr
†These authors contributed equally to this work.
Volume 6, Number 3, Pages 107-115, September 2022.
Journal of Animal Breeding and Genomics 2022, 6(3), 107-115. https://doi.org/10.12972/jabng.20220012
Received on July 04, 2022, Revised on September 19, 2022, Accepted on September 19, 2021, Published on September 30, 2022.
Copyright © 2022 Korean Society of Animal Breeding and Genetics.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0).
Olive flounder (Paralichthys olivaceus) is one of the most produced fish, accounting for 46.2% (37,240 metric tons) of total fish farming yield in Korea. Flounder is vulnerable to viral hemorrhagic septicemia (VHS) which makes fish farmers struggle. Viral Hemorrhagic Septicemia Virus (VHSV) is an RNA virus sustaining its infectivity, especially at low temperatures (8-15°C). In order to minimize the damage from VHSV, several studies were conducted. However, the genetic factor of resistance to VHSV is not well known to date. Quantitative trait loci (QTL) analysis is an efficient analysis in aspects of detecting loci that influence quantitative traits. We conducted a quantitative trait locus (QTL) analysis by constructing a genetic linkage group. 23 linkage groups were constructed and it’s reliable according to the previous study that suggested flounder has 2n=48 chromosome. Bivariate phenotypes (dead/alive) were adapted and 5 pseudo markers were identified as QTL. A total of 7 markers were nearby 5 pseudo markers, located in linkage groups 8, 13, and 16. Although it can be more delicately accurate results if the bivariate phenotype information were f ixed by extra environment effects, those markers are valuable to be candidates for representing the resistance of VHSV in terms of f lounder.
Genetic map, Olive flounder, QTL analysis, VHSV
본 논문은 2022년도 해양수산부 재원으로 국립수산과학원(과제명: 양식생물 육종품종 개발 및 산업화, 과제번호: R2022001) 및 해양수산과학기술진흥원(과제명: 수산종자산업 디지털혁신 기술개발, 과제번호: 20220570)의 지원을 받아 수행된 연구임.
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