Journal of Animal Breeding and Genomics (J Anim Breed Genom)
SeungYeon Youk, Mingue Kang, Hyoim Jeon, Chankyu Park*
Department of stem cell and regenerative biotechnology, Konkuk University, Gwangjin-gu, Seoul, South Korea
Correspondence to Chankyu Park, E-mail: chankyu@konkuk.ac.kr
Volume 5, Number 3, Pages 99-106, September 2021.
Journal of Animal Breeding and Genomics 2021, 5(3), 99-106. https://doi.org/10.12972/jabng.20210010
Received on 16 September, 2021, Revised on 27 September, 2021, Accepted on 28 September, 2021, Published on 30 September, 2021.
Copyright © 2021 Korean Society of Animal Breeding and Genetics.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0).
The genetic diversity of the major histocompatibility complex (MHC) molecules of pigs has not been thoroughly characterized. In this study, we successfully typed SLA-2, a pig MHC class I gene, from 10 pigs of five different breeds using a high-resolution typing method. We identified a total of 14 SLA-2 alleles including 2 previously unreported alleles and reported to IPD-MHC SLA database. These new alleles showed 1 and 29 nucleotide differences from the closely related alleles, SLA-2*10:01 and SLA-2*13:02, respectively. The information of SLA new alleles should enrich our understanding the diversity of MHC diversity in pigs.
Direct sequencing, MHC class I, MHC typing, pigs, SLA-2
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